Vascade vascular closure system provides rapid hemostasis for interventional and diagnostic procedures and is the only closure device proven safer than manual compression in a randomized clinical trial with zero major complications. The Vascade system works by allowing your physician to deliver a collagen patch at the puncture site in the tissue surrounding the vessel. The precise placement of the collagen is accomplished by placing a small collapsible mesh disc against the inside of the vessel wall, which provides temporary hemostasis.