Your choice of sealant matters. DuraSeal exact is the spine sealant that strengthens your repair and supports the body's natural healing process. With demonstrated superior tissue adherence versus fibrin glue, DuraSeal exact is engineered for appropriate strength and optimal duration for the tighter confines and higher pressures of the spine. DuraSeal exact is indicated as an adjunct to sutured dural repair during spine surgery to provide watertight closure. It is a polymer composed of two solutions, a polyethylene glycol (PEG) ester solution and a trilysine amine solution. When mixed together, these precursors cross link to form a hydrogel sealant that creates a quick and effective watertight seal that lasts both intraoperatively and through the critical healing period.